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      MENUMENU
      • METAL SENSITIVITY
        • Implant hypersensitivity
        • Metal exposure
          • Nickel allergy
          • Titanium hypersensitivity
          • Mercury allergy
          • Galvanic corrosion
          • Metal devices
          • Questionnaires
        • Associated diseases
        • Patient testimonial
          • Gaynor Mitchell
          • Danelle Filby
          • Patricia Hart
          • Kathryn Clements
          • Ann Arnecke
          • Dr Pierre Mason
          • Linda Reisersen
          • Hanne Koplev
          • Sue Collins
          • Louis Despres
          • Jane Cole
        • FDA statement & BSEM conference
      • TESTING
        • Allergens tested
        • Test FAQs
        • US/Canada FAQs
        • Phlebotomy service options in the US
        • Sending blood
          • Phlebotomy guide
        • Sample report
        • MELISA vs LTT
      • HCPs
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          • Galvanic corrosion
        • Orthopaedics
      • RESEARCH
        • Articles
        • Case reports
        • Research projects
      • ABOUT
        • Our team
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        • Laboratory licensing opportunities
      • CONTACT
        • Head Offices
        • MELISA laboratories
        • Clinics providing access to MELISA testing
        • Contact form
        • US/Canada FAQs
    • Order test kit
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    News

    MELISA Spring Newsletter

    April 14, 2020 - melisa_wpa

    Comments are off for this post.

    The latest Newsletter is out, the MELISA team are focusing on maintaining a healthy immune system and advice from functional medicine doctors.

    MELISA Spring Newsletter 2020

    1st International Master Class of Ceramic Implantology 7-8 February MELISA Summer Newsletter

    melisa_wpa

    Related posts:

    melisa

    MELISA is a blood test to aid the diagnosis of metal hypersensitivity. It is used worldwide by healthcare professionals to help determine whether patients are hypersensitive to metals commonly used in dental restorations or medical implants. Further test applications include Lyme disease.

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    MELISA NEWSLETTER (6 per year)

    Melisa Diagnostics

    6 days ago

    Melisa Diagnostics

    In this podcast, Dr Scott Schroeder shares his experience of metal hypersensitivity and of removing over a 1,000 metal implants from patients who complained of onset of health problems after receiving metal implants. His surgeon colleagues call metal allergy a "rare occurrence" but based on in his observations, 3-4% of patients may experience life-changing debilitating symptoms after implant placement. The goods news is that many symptoms disappear after metal removal.
    soundcloud.com/healthsolutionsshawnjanet/ep-198-are-metal-implants-from-surgery-causing-allergic-...
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    Ep 198: Are Metal Implants From Surgery Causing Allergic Responses? - Dr. Scott Schroeder

    soundcloud.com

    Could metal in your body from previous surgeries be causing issues? Please welcome surgeon Scott Schroeder MD to discuss his findings with potential allergic responses to metal after surgery or dental
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    Melisa Diagnostics

    4 weeks ago

    Melisa Diagnostics

    “I have repeatedly found myself minimized, marginalized and treated as a [second] class citizen whenever I inquired on the little known issue”. This is a quote from one patient interviewed by Dr. Dzifa Dordunoo, assistant professor at the University of Victoria, on the issues facing patients who develop hypersensitivity reactions after being implanted with metal-containing medical devices. Based on the answer given, Dr Dordunoo highlights the need to inform patients of the metal composition of the devices implanted and also include pre-op screening question about previous reactions to metals.

    www.youtube.com/watch?v=ItdSr7gV_oU
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    Consenting patients about metal hypersensitivity

    www.youtube.com

    In this video, I discuss the findings of our qualitative study on what information patients want to know before giving consent for implantable devices with m...

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    Melisa Diagnostics

    3 months ago

    Melisa Diagnostics

    On International #womeninscience Day we remember Prof Vera Stejskal who is sadly no longer with us. We miss her unquenchable optimism, can-do attitude, thirst for knowledge and burning desire to bring about change so that people who are suffering from metal hypersensitivity get the support and treatment they need. Vera, we do our best to follow in your footsteps but your shoes are hard to fill.Dr Vera Stejskal, inventor of MELISA testing, has passed away after a brief period of illness. A pioneer in the field of immunotoxicology, her groundbreaking research into the connection between metal induced inflammation and chronic disease has helped hundreds of patients regain their health. She was born in Prague and fled to Sweden after the 1968 invasion of Czechoslovakia.

    She started work at the Department of Immunology at the University of Stockholm where she became Associated Professor of Immunology in 1976. She then joined Astra, running its immunotoxicology division where one of her first assignments was to have a final look at a new drug that was being tested: omeprazole. Studies had showed necrotizing vasculitis in the small intestine of some dogs, and the project looked set to be terminated. The group she led was able to prove that the drug had no such side effects and the drug went on to become Losec, the best-selling drug in the world.

    As a next project, Dr Stejskal was asked to develop a test for the diagnosis of drug allergy among workers in Astra’s pharmaceutical factories. They had noticed that some workers complained of allergy related symptoms while working in the factories – symptoms that would completely disappear during holidays. Dr Stejskal applied the lymphocyte transformation test, originally developed in the 1960s for evaluating histocompatible class II HLA antigens. She modified it for class II antigen typing and also applied it extensively to detecting type IV allergies to drugs. As of today, Astra is still using this blood test to ensure workers are not exposed to drugs that might be inducing sensitivities.

    In 1990 a colleague of Dr Stejskal, dermatologist Dr Margit Forsbeck, asked to try the new test on patients who suspected their symptoms were caused by their dental metal fillings, mainly amalgam. At the time, the only option was patch testing – as a skin test not very reliable for testing metal allergy. Dr Stejskal compared lymphocyte reactions between patients and healthy controls and found to her surprise that patients’ lymphocytes reacted more frequently and strongly to mercury salts than controls’. The results were published in The Journal of Clinical Immunology in 1996 (Mercury-specific lymphocytes: An indication of mercury allergy in man).

    In 1999, Astra and Zeneca group merged to form AstraZeneca. Since there were now three immunotoxicological departments, Dr Stejskal decided to leave the company and pursue the test on her own. Astra was a pharmaceutical rather than a diagnostic company, and had no interest in developing the test further. She patented it under the name MELISA, and acronym for Memory Lymphocyte Immuno Stimulation Assay.

    She then devoted her life to the test, and was affiliated with the Karolinska Institute, Stockholm. From 2004 to 2012 she was an associated professor at the Department of Immunology and Microbiology, First Medical faculty at Charles University, Prague, Czech Republic, where she directed research on the pathological role of metals in chronic diseases.

    Dr Stejskal and colleagues worked tirelessly to prove the validity of the MELISA, and that its test results were repeatable, reliable and useful. The test promised to open a new field of medicine, investigating the link between chronic disease and an allergy to an everyday metal exposure. The allergies were rare, but for those affected they could be debilitating – yet once their condition was diagnosed, the patient’s health could improve with removal or replacement of allergy causing metals. Dr Stejskal organised conferences to educate and facilitate cooperation between researchers, doctors and dentist, and dentistry especially was a key part of the treatment protocol. Many professional relationships turned into close friendships.

    MELISA started to be performed under license by certified laboratories worldwide and university researchers were using the test in their work. In total, Dr Stejskal published more than 100 scientific articles and was frequently a speaker on the subject of immunotoxicity of heavy and transitional metals and the link to the development/aggravation of allergy and autoimmunity. She was also board member of European Academy of Environmental Medicine and scientific member of ESAAM and I-GAP.

    Dr Stejskal never planned to retire – for her, her work was her passion in life. She believed rigorous scientific studies would bring a better, healthier world. The MELISA test is her medical legacy, and will now continue without her. She has left us to go on to further discoveries and adventures.
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    Melisa Diagnostics

    3 months ago

    Melisa Diagnostics

    Allergy to gold is a rare condition, but in some it can play an important role in the development of health issues. In this case, a 64-year-old female was reevaluated for contact dermatitis; she had developed rashes after starting a new medication and had oral lichenoid lesions in the mouth. Patch testing showed a positive allergic reaction to gold and it turned out that her dental metal crowns has a significant gold content. Her dentist recommended removal of the gold-containing crowns. Previous studies on patients with oral lichen planus and amalgam fillings concluded that there is a likely therapeutic benefit in removal of the amalgam in most situations.
    www.cureus.com/articles/84477-gold-dental-implant-induced-oral-lichen-planus
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    Gold Dental Implant-Induced Oral Lichen Planus

    www.cureus.com

    Lichen planus is a chronic inflammatory cutaneous and mucosal disease mostly affecting middle-aged individuals. The etiology of lichen planus is unknown, but current literature suggests that it is an ...
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    Melisa Diagnostics

    4 months ago

    Melisa Diagnostics

    This article makes it absolutely clear why manufacturers of medical devices must fully disclose all metals used. These surgeons knew about their patient's nickel allergy and chose a stainless steel stent. It was only when the patient experienced a reoccurrence of his previous symptoms that the vascular surgeons discovered that stainless steel is made up of between 10-16% nickel. The stent was removed and the patient's symptoms resolved. The surgeons say "Each manufacturer of vascular stents has used proprietary metallurgy in the production of its stent. Checking with the manufacturer as to the stent metallurgy and considering alternatives to treatment need to be addressed before use of stainless steel stents in those patients with nickel or other metal allergies.". Although this is true, it would save a great deal of suffering if manufacturers clearly listed the exact composition in the first place. ... See MoreSee Less

    Systemic hypersensitivity reaction to endovascular stainless steel stent

    www.sciencedirect.com

    Endovascular intervention has become the mainstay for treatment of most patients suffering from peripheral vascular disease. We describe a patient wit...
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